{"id":11712,"date":"2026-09-03T11:31:16","date_gmt":"2026-09-03T02:31:16","guid":{"rendered":"https:\/\/kojihifu.com\/english\/?p=11712"},"modified":"2026-09-03T11:31:17","modified_gmt":"2026-09-03T02:31:17","slug":"fat-dissolving-injection-tokyo-cost","status":"publish","type":"post","link":"https:\/\/kojihifu.com\/english\/fat-dissolving-injection-tokyo-cost\/","title":{"rendered":"Fat Dissolving Injection Tokyo: Cost and Areas Treated"},"content":{"rendered":"<p><script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"MedicalWebPage\",\"@id\":\"https:\/\/kojihifu.com\/english\/fat-dissolving-injection-tokyo-cost\/#webpage\",\"url\":\"https:\/\/kojihifu.com\/english\/fat-dissolving-injection-tokyo-cost\/\",\"name\":\"Fat Dissolving Injection Tokyo: Cost and Areas Treated\",\"inLanguage\":\"en\",\"isPartOf\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#website\"},\"about\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#clinic-biotope\"},\"reviewedBy\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#physician-karibe\"},\"lastReviewed\":\"2026-09-03\"},{\"@type\":[\"Article\",\"MedicalWebPage\"],\"@id\":\"https:\/\/kojihifu.com\/english\/fat-dissolving-injection-tokyo-cost\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/kojihifu.com\/english\/fat-dissolving-injection-tokyo-cost\/#webpage\"},\"headline\":\"Fat Dissolving Injection Tokyo: Cost and Areas Treated\",\"url\":\"https:\/\/kojihifu.com\/english\/fat-dissolving-injection-tokyo-cost\/\",\"inLanguage\":\"en\",\"author\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#physician-karibe\"},\"reviewedBy\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#physician-karibe\"},\"publisher\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#organization\"},\"mainEntityOfPage\":{\"@id\":\"https:\/\/kojihifu.com\/english\/fat-dissolving-injection-tokyo-cost\/#webpage\"},\"description\":\"Fat dissolving injection in Tokyo: what it costs, which areas are treated, realistic results and downtime, plus who is a candidate. Ask our English team.\",\"datePublished\":\"2026-09-03\",\"dateModified\":\"2026-09-03\",\"lastReviewed\":\"2026-09-03\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/kojihifu.com\/english\/fat-dissolving-injection-tokyo-cost\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/kojihifu.com\/english\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Skin & Dermatology\",\"item\":\"https:\/\/kojihifu.com\/english\/column\/skin-dermatology\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Fat Dissolving Injection Tokyo: Cost and Areas Treated\",\"item\":\"https:\/\/kojihifu.com\/english\/fat-dissolving-injection-tokyo-cost\/\"}]}]}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"How many sessions will I need?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"In the FDA registration trials, 59 percent of subjects received all six permitted sessions, spaced at least one month apart. Your own number depends on the area size and your response, and should be reassessed at each visit rather than fixed in advance.\"}}, {\"@type\": \"Question\", \"name\": \"Will the fat come back?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"The mechanism destroys fat cells rather than shrinking them, and three-year follow-up data indicates 82.4 percent of responders maintained their improvement. However, significant weight gain can still enlarge remaining fat cells in the area.\"}}, {\"@type\": \"Question\", \"name\": \"Is it covered by Japanese health insurance?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"No. It is self-pay cosmetic treatment. Because the products are unapproved in Japan, any adverse event is also outside the national Relief System for Sufferers from Adverse Drug Reactions \u2014 your clinic is required to tell you this.\"}}, {\"@type\": \"Question\", \"name\": \"Can I have it done as a visitor to Tokyo?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"It is possible, but consider the timing: swelling and bruising are common and can last days to weeks, and a full course requires monthly visits. Discuss your travel schedule at consultation.\"}}]}<\/script><\/p>\n<h2>Fat Dissolving Injection in Tokyo: Cost, Areas Treated and What to Realistically Expect<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 Fat Dissolving Injection in Tokyo: Cost, Areas Treated and W\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/09\/pexels_16131210_1788394690.webp\" alt=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 Fat Dissolving Injection in Tokyo: Cost, Areas Treated and W\" \/><\/figure>\n<p>If you have been staring at a stubborn pocket under your chin that stays put no matter how carefully you eat or how often you train, you are far from alone \u2014 and the frustration is entirely reasonable, because <strong>subcutaneous fat<\/strong> in small, localised areas responds poorly to diet and exercise.<\/p>\n<p><strong>Fat dissolving injections<\/strong> (also called injection lipolysis or mesotherapy) are one of the most frequently asked-about options at Tokyo clinics.<\/p>\n<p>This article explains what the treatment actually does, which body areas are realistically treatable, what the published clinical evidence shows, and how cost and downtime work in Japan.<\/p>\n<p><strong>What you&#8217;ll learn in this article:<\/strong><\/p>\n<ul>\n<li>How deoxycholic acid fat dissolving injections work, and why the mechanism matters<\/li>\n<li>The regulatory position in Japan versus the United States \u2014 a distinction many articles blur<\/li>\n<li>Which areas are commonly treated, and which area has genuine phase 3 evidence behind it<\/li>\n<li>Realistic results, session counts, and the downtime figures from the manufacturer&#8217;s clinical trials<\/li>\n<li>How cost is structured in Tokyo, and who is and is not a suitable candidate<\/li>\n<\/ul>\n<div class=\"kjmc-en-booking-inline\" style=\"background: #f7fbf7; border: 1px solid #d5e6d8; border-radius: 10px; padding: 16px 20px; margin: 26px 0; text-align: center;\">\n<p style=\"margin: 0 0 12px; color: #1a3a1f; font-size: 0.95em; line-height: 1.65;\"><strong>Have a question about this treatment?<\/strong><br \/>\nMessage us on LINE or WhatsApp \u2014 our English-speaking team usually replies the same day.<\/p>\n<p style=\"margin: 0; line-height: 1;\"><a style=\"display: inline-flex; align-items: center; gap: 8px; background: #06C755; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/line.me\/R\/ti\/p\/@710uitns?ts=05311801&amp;oat_content=url#~\" target=\"_blank\" rel=\"noopener noreferrer\">Book via LINE<\/a><br \/>\n<a style=\"display: inline-flex; align-items: center; gap: 8px; background: #25D366; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/whatsapp.com\/channel\/0029VbCA1v85K3zY4MLX2a1h\" target=\"_blank\" rel=\"noopener noreferrer\">Message on WhatsApp<\/a><\/p>\n<\/div>\n<h2>What Is a Fat Dissolving Injection?<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 What Is a Fat Dissolving Injection\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/09\/pexels_32532049_1788394692.webp\" alt=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 What Is a Fat Dissolving Injection\" \/><\/figure>\n<p>A fat dissolving injection is a series of small injections placed directly into a subcutaneous fat pad, using a solution intended to break down fat cells locally. The most extensively studied active ingredient is <strong>deoxycholic acid<\/strong>, a bile acid the human body produces naturally to help absorb dietary fat.<\/p>\n<h3>How deoxycholic acid works<\/h3>\n<p>According to the US prescribing information for the deoxycholic acid product<strong> KYBELLA<\/strong>, the drug is <em>cytolytic<\/em> \u2014 when injected into tissue, it physically disrupts the fat cell membrane. The destroyed cells are then cleared by the body&#8217;s normal inflammatory and metabolic processes over the following weeks.<\/p>\n<p>Because the cells are destroyed rather than shrunk, the reduction is intended to be lasting, provided overall body weight remains stable. This is a different mechanism from skin tightening devices, which act on collagen and connective tissue rather than on fat volume.<\/p>\n<h3>Approval status in Japan and abroad \u2014 please read this carefully<\/h3>\n<p>Deoxycholic acid injection received its initial US Food and Drug Administration approval in <strong>2015<\/strong>, indicated for the improvement of moderate to severe fullness associated with <strong>submental fat (under the chin) in adults<\/strong>. The same label states plainly that safe and effective use outside the submental region has not been established and is not recommended.<\/p>\n<p>US approval is not Japanese approval. In Japan, fat dissolving injection products are provided as self-pay (\u81ea\u7531\u8a3a\u7642) treatment using preparations that have not been approved under Japan&#8217;s Pharmaceuticals and Medical Devices Act, typically obtained through a physician&#8217;s personal import.<\/p>\n<p>Japan&#8217;s Ministry of Health, Labour and Welfare Medical Advertising Guideline (last revised 13 September 2024) requires clinics using unapproved drugs in self-pay care to disclose, among other things, that the product is unapproved, how it was obtained, its overseas approval status, and \u2014 importantly \u2014 that any resulting health damage falls <strong>outside<\/strong> the national Relief System for Sufferers from Adverse Drug Reactions. A clinic that does not tell you this is not meeting the guideline.<\/p>\n<h2>Areas Commonly Treated<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 Areas Commonly Treated\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/09\/pexels_7446679_1788394693.webp\" alt=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 Areas Commonly Treated\" \/><\/figure>\n<p>In Japanese aesthetic practice, fat dissolving injections are most often requested for:<\/p>\n<ul>\n<li><strong>Under the chin (submental area)<\/strong> \u2014 the &#8220;double chin&#8221;; the only area with regulator-reviewed phase 3 evidence<\/li>\n<li><strong>Lower face, jawline and cheeks<\/strong> \u2014 for softening a heavy or rounded facial contour<\/li>\n<li><strong>Upper arms<\/strong><\/li>\n<li><strong>Abdomen and flanks<\/strong><\/li>\n<li><strong>Inner and outer thighs, and above the knees<\/strong><\/li>\n<li><strong>Bra line and upper back<\/strong><\/li>\n<\/ul>\n<p>Be aware of the evidence gradient here. Treatment of body areas other than under the chin is off-label use, supported by clinical experience rather than by the large randomised trials that underpin the submental indication. A responsible consultation should say so rather than presenting every area as equally proven.<\/p>\n<h2>Expected Results and How Long They Last<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 Expected Results and How Long They Last\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/09\/pexels_13060585_1788394694.webp\" alt=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 Expected Results and How Long They Last\" \/><\/figure>\n<p>In the two pooled double-blind, placebo-controlled trials submitted to the FDA (513 treated subjects versus 506 placebo), 70.0 percent of treated patients in one trial achieved at least a one-grade improvement on the combined clinician and patient rating scale, compared with roughly 18 to 22 percent on placebo.<\/p>\n<p>In an MRI sub-study of 449 subjects, 43 percent of treated patients showed at least a 10 percent reduction in submental fat volume, versus 5 percent of placebo patients. Note what that figure means: measurable, meaningful reduction \u2014 not the elimination of a fat pad.<\/p>\n<p>Results build slowly. Fifty-nine percent of trial subjects required all six permitted treatment sessions, spaced at least one month apart. Expecting a visible change after a single session is the single most common source of disappointment.<\/p>\n<p>On durability, a three-year follow-up of REFINE phase 3 participants (224 patients) published in <em>Aesthetic Surgery Journal<\/em> in 2021 reported that 82.4 percent of treated responders maintained their improvement at year three, and clinical reports indicate patient satisfaction was largely sustained over the same period.<\/p>\n<h2>Fat Dissolving Injection Cost in Tokyo<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 Fat Dissolving Injection Cost in Tokyo\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/09\/pexels_7581583_1788394694.webp\" alt=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 Fat Dissolving Injection Cost in Tokyo\" \/><\/figure>\n<p>Fat dissolving injection is self-pay treatment in Japan and is not covered by national health insurance, so the full cost is borne by the patient. Pricing in Tokyo is usually structured per vial, per treatment area, or as a multi-session course.<\/p>\n<p>Three factors drive the total more than the headline per-session figure: the <strong>size of the area<\/strong> (an abdomen requires far more product than a submental pocket), the <strong>number of sessions<\/strong> you actually need, and the <strong>product used<\/strong>, since concentration and formulation vary considerably between preparations.<\/p>\n<p>Because the trial protocol permitted up to six sessions, budget realistically for a course rather than a single appointment when comparing quotes.<\/p>\n<p>Please see the clinic&#8217;s official price page or contact us for a current quote. For an accurate quote, please book a consultation.<\/p>\n<div class=\"kjmc-en-booking-inline\" style=\"background: #f7fbf7; border: 1px solid #d5e6d8; border-radius: 10px; padding: 16px 20px; margin: 26px 0; text-align: center;\">\n<p style=\"margin: 0 0 12px; color: #1a3a1f; font-size: 0.95em; line-height: 1.65;\"><strong>Have a question about this treatment?<\/strong><br \/>\nMessage us on LINE or WhatsApp \u2014 our English-speaking team usually replies the same day.<\/p>\n<p style=\"margin: 0; line-height: 1;\"><a style=\"display: inline-flex; align-items: center; gap: 8px; background: #06C755; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/line.me\/R\/ti\/p\/@710uitns?ts=05311801&amp;oat_content=url#~\" target=\"_blank\" rel=\"noopener noreferrer\">Book via LINE<\/a><br \/>\n<a style=\"display: inline-flex; align-items: center; gap: 8px; background: #25D366; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/whatsapp.com\/channel\/0029VbCA1v85K3zY4MLX2a1h\" target=\"_blank\" rel=\"noopener noreferrer\">Message on WhatsApp<\/a><\/p>\n<\/div>\n<h2>What to Expect: Before, During and After<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 What to Expect: Before, During and After\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/09\/pexels_4586708_1788394695.webp\" alt=\"Fat dissolving injection Tokyo: cost and areas tre \u2014 What to Expect: Before, During and After\" \/><\/figure>\n<p>At consultation, the treating physician should assess whether your concern is genuinely subcutaneous fat rather than skin laxity, muscle bulk, or salivary gland prominence \u2014 these look similar to the untrained eye but respond to entirely different treatments.<\/p>\n<p>The injection itself takes roughly 15 to 20 minutes. Topical or local anaesthesia and cold packs were permitted during the clinical trials and are commonly used.<\/p>\n<p>Downtime is real and should not be minimised. In the pooled FDA trial data, injection site swelling occurred in 87 percent of treated subjects, bruising in 72 percent, pain in 70 percent and numbness in 66 percent. Reactions persisting beyond 30 days included numbness in 42 percent and swelling in 20 percent.<\/p>\n<p>Less common but more serious risks in the same dataset included marginal mandibular nerve paresis \u2014 a temporarily uneven smile \u2014 in 4 percent, and difficulty swallowing in 2 percent. Injections placed too superficially can cause skin ulceration and necrosis. This is precisely why anatomical precision, and a physician who knows where the nerve and salivary glands sit, matters more than the product brand.<\/p>\n<h3>Who is a good candidate \u2014 and who should avoid it<\/h3>\n<p>Good candidates typically have a discrete, pinchable fat pocket, reasonably good skin elasticity, a stable body weight, and realistic expectations about gradual change over several months.<\/p>\n<p>The treatment is contraindicated where there is infection at the injection site. It should be approached with particular caution in patients on antiplatelet or anticoagulant therapy or with clotting abnormalities, and in those with pre-existing swallowing difficulty. It is not a weight-loss treatment, and it does not correct sagging skin.<\/p>\n<p>At BIOTOPE CLINIC in Shirokanedai, a meaningful share of consultations for &#8220;double chin&#8221; turn out on examination to involve skin laxity or platysmal banding as much as fat volume \u2014 which is why the assessment, not the injection, is the part that determines whether you will be happy with the outcome.<\/p>\n<h2>What People Often Get Wrong<\/h2>\n<p><strong>Misconception 1: &#8220;It&#8217;s FDA-approved, so it must be approved in Japan and safe for any body area.&#8221;<\/strong> Two errors in one sentence. FDA approval covers submental fat in adults only, and the label explicitly states that use outside the submental region has not been established. Separately, FDA approval carries no weight under Japanese law \u2014 products used here are unapproved under the PMD Act, and Japan&#8217;s Medical Advertising Guideline requires clinics to state that adverse events are outside the national relief system.<\/p>\n<p><strong>Misconception 2: &#8220;It&#8217;s a lunchtime treatment with no downtime.&#8221;<\/strong> The manufacturer&#8217;s own trial data contradicts this: swelling in 87 percent, bruising in 72 percent, and numbness lasting more than 30 days in 42 percent of subjects. Plan around a visible recovery period, particularly for facial treatment.<\/p>\n<p>These distinctions matter commercially as well as clinically. Consultations about cosmetic medical services logged by Japan&#8217;s National Consumer Affairs Center rose to 10,744 in FY2024 from 6,281 the previous year, with inadequate explanation of risk a recurring theme.<\/p>\n<h2>How It Compares With Other Contouring Options<\/h2>\n<table style=\"border-collapse: collapse; width: 100%; margin: 20px 0; font-size: 0.95em; border: 1px solid #ccc;\">\n<thead>\n<tr>\n<th style=\"border: 1px solid #ccc; padding: 10px 12px; background: #f1faf3; text-align: left; font-weight: bold;\">Option<\/th>\n<th style=\"border: 1px solid #ccc; padding: 10px 12px; background: #f1faf3; text-align: left; font-weight: bold;\">Primary target<\/th>\n<th style=\"border: 1px solid #ccc; padding: 10px 12px; background: #f1faf3; text-align: left; font-weight: bold;\">Typical downtime<\/th>\n<th style=\"border: 1px solid #ccc; padding: 10px 12px; background: #f1faf3; text-align: left; font-weight: bold;\">Best suited to<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Fat dissolving injection<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Subcutaneous fat volume<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Days to weeks (swelling, bruising, numbness)<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Discrete fat pockets with good skin quality<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">HIFU (focused ultrasound)<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Skin laxity and tissue tightening<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Minimal<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Mild sagging rather than fat volume<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Morpheus8 (RF microneedling)<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Skin texture and dermal tightening<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Redness for several days<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Skin quality alongside contour concerns<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Surgical fat removal<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Larger fat volumes<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Weeks; surgical recovery<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Volume too large for injection to address<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>In practice these are complementary rather than competing. HIFU and Morpheus8 are both available at BIOTOPE CLINIC in Shirokanedai \u2014 feel free to ask during a consultation with Dr. Karibe whether a combined approach suits your anatomy better than injections alone.<\/p>\n<h2>Where to Get Fat Dissolving Injections in Tokyo<\/h2>\n<p>Within our clinic group, both BIOTOPE CLINIC (Shirokanedai, Minato-ku) and Kojimachi Dermatology &amp; Plastic Surgery Clinic (Ichigaya, Chiyoda-ku) offer English-language consultation with Dr. Jun Karibe&#8217;s team. Fat dissolving injection is handled at BIOTOPE CLINIC in Shirokanedai. Bookings and enquiries in English: LINE or WhatsApp.<\/p>\n<p>Kojimachi Dermatology &amp; Plastic Surgery Clinic, the group&#8217;s main office, focuses on insurance-covered general dermatology and general and aesthetic plastic surgery \u2014 the right destination if your concern turns out to be a skin condition rather than a contouring one.<\/p>\n<h2>Frequently Asked Questions<\/h2>\n<dl class=\"kj-faq\">\n<dt>Q. How many sessions will I need?<\/dt>\n<dd>In the FDA registration trials, 59 percent of subjects received all six permitted sessions, spaced at least one month apart. Your own number depends on the area size and your response, and should be reassessed at each visit rather than fixed in advance.<\/dd>\n<dd><\/dd>\n<dt>Q. Will the fat come back?<\/dt>\n<dd>The mechanism destroys fat cells rather than shrinking them, and three-year follow-up data indicates 82.4 percent of responders maintained their improvement. However, significant weight gain can still enlarge remaining fat cells in the area.<\/dd>\n<dd><\/dd>\n<dt>Q. Is it covered by Japanese health insurance?<\/dt>\n<dd>No. It is self-pay cosmetic treatment. Because the products are unapproved in Japan, any adverse event is also outside the national Relief System for Sufferers from Adverse Drug Reactions \u2014 your clinic is required to tell you this.<\/dd>\n<dd><\/dd>\n<dt>Q. Can I have it done as a visitor to Tokyo?<\/dt>\n<dd>It is possible, but consider the timing: swelling and bruising are common and can last days to weeks, and a full course requires monthly visits. Discuss your travel schedule at consultation.<\/dd>\n<\/dl>\n<div class=\"kjmc-en-booking-inline\" style=\"background: #f7fbf7; border: 1px solid #d5e6d8; border-radius: 10px; padding: 16px 20px; margin: 26px 0; text-align: center;\">\n<p style=\"margin: 0 0 12px; color: #1a3a1f; font-size: 0.95em; line-height: 1.65;\"><strong>Have a question about this treatment?<\/strong><br \/>\nMessage us on LINE or WhatsApp \u2014 our English-speaking team usually replies the same day.<\/p>\n<p style=\"margin: 0; line-height: 1;\"><a style=\"display: inline-flex; align-items: center; gap: 8px; background: #06C755; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/line.me\/R\/ti\/p\/@710uitns?ts=05311801&amp;oat_content=url#~\" target=\"_blank\" rel=\"noopener noreferrer\">Book via LINE<\/a><br \/>\n<a style=\"display: inline-flex; align-items: center; gap: 8px; background: #25D366; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/whatsapp.com\/channel\/0029VbCA1v85K3zY4MLX2a1h\" target=\"_blank\" rel=\"noopener noreferrer\">Message on WhatsApp<\/a><\/p>\n<\/div>\n<h2>Summary<\/h2>\n<p>Fat dissolving injection can produce a modest, measurable and durable reduction in localised fat, with the strongest evidence by far for the area under the chin.<\/p>\n<p>It is not a weight-loss treatment, not a substitute for skin tightening, and not downtime-free.<\/p>\n<p>In Japan it is self-pay treatment using products unapproved under the PMD Act, which makes the quality of your consultation \u2014 honest discussion of evidence, risk, session count and cost \u2014 the most important variable in the whole process.<\/p>\n<p>If you have questions about fat dissolving injections, both <strong>BIOTOPE CLINIC<\/strong> (Shirokanedai, Minato-ku) and <strong>Kojimachi Dermatology &amp; Plastic Surgery Clinic<\/strong> (Ichigaya, Chiyoda-ku) offer English-language consultation with Dr. Karibe and his team. Fat dissolving injection is primarily handled at BIOTOPE CLINIC in Shirokanedai. English enquiries: LINE or WhatsApp.<\/p>\n<div class=\"kjmc-en-booking-box\" style=\"background: linear-gradient(135deg,#f1faf3 0%,#e6f3ea 100%); border-radius: 14px; padding: 32px 24px; margin: 36px 0 24px; border: 1px solid #c5dccd; text-align: center;\">\n<h3 style=\"margin: 0 0 8px; color: #3a6e3a; border: none; padding: 0; font-size: 1.3em;\">24\/7 Consultation &amp; Booking<\/h3>\n<div style=\"width: 48px; height: 2px; background: #3a6e3a; margin: 0 auto 22px;\"><\/div>\n<p style=\"margin: 0 0 12px; color: #1a3a1f; font-size: 1.1em; font-weight: bold;\">Book a Consultation or Treatment<\/p>\n<p style=\"margin: 0 0 24px; color: #2c4a35; line-height: 1.75;\">Our English-speaking team responds via LINE or WhatsApp \u2014 usually the same day.<\/p>\n<p style=\"margin: 0 0 10px; line-height: 1;\"><a style=\"display: inline-flex; align-items: center; justify-content: center; gap: 10px; background: #06C755; color: #fff; padding: 14px 32px; border-radius: 10px; text-decoration: none; font-weight: bold; font-size: 1.02em; box-shadow: 0 2px 8px rgba(6,199,85,0.25); min-width: 240px; white-space: nowrap;\" href=\"https:\/\/line.me\/R\/ti\/p\/@710uitns?ts=05311801&amp;oat_content=url#~\" target=\"_blank\" rel=\"noopener noreferrer\">Book via LINE<\/a><\/p>\n<p style=\"margin: 0; line-height: 1;\"><a style=\"display: inline-flex; align-items: center; justify-content: center; gap: 10px; background: #25D366; color: #fff; padding: 14px 32px; border-radius: 10px; text-decoration: none; font-weight: bold; font-size: 1.02em; box-shadow: 0 2px 8px rgba(37,211,102,0.25); min-width: 240px; white-space: nowrap;\" href=\"https:\/\/whatsapp.com\/channel\/0029VbCA1v85K3zY4MLX2a1h\" target=\"_blank\" rel=\"noopener noreferrer\">Message on WhatsApp<\/a><\/p>\n<\/div>\n<h2>References<\/h2>\n<ol>\n<li>U.S. Food and Drug Administration. KYBELLA (deoxycholic acid) injection, for subcutaneous use \u2014 Highlights of Prescribing Information. Initial U.S. Approval 2015; revised 2022. <a href=\"https:\/\/www.fda.gov\/\">https:\/\/www.fda.gov\/<\/a><\/li>\n<li>Humphrey S, Cohen JL, Bhatia AC, Green LJ, Green JB, Bowen B. Improvements in Submental Contour up to 3 Years After ATX-101: Efficacy and Safety Follow-Up of the Phase 3 REFINE Trials. Aesthetic Surgery Journal. 2021;41(11):NP1532\u2013NP1539.<\/li>\n<li>Ministry of Health, Labour and Welfare, Japan. Medical Advertising Guideline (\u533b\u7642\u5e83\u544a\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3), last revised 13 September 2024. <a href=\"https:\/\/www.mhlw.go.jp\/\">https:\/\/www.mhlw.go.jp\/<\/a><\/li>\n<li>Pharmaceuticals and Medical Devices Agency, Japan. Relief System for Sufferers from Adverse Drug Reactions. <a href=\"https:\/\/www.pmda.go.jp\/\">https:\/\/www.pmda.go.jp\/<\/a><\/li>\n<li>National Consumer Affairs Center of Japan. Cosmetic medical services: consultation statistics. Updated 31 July 2026. <a href=\"https:\/\/www.kokusen.go.jp\/\">https:\/\/www.kokusen.go.jp\/<\/a><\/li>\n<\/ol>\n<h2>Related Articles<\/h2>\n<p>You may also find these articles useful.<\/p>\n<ul>\n<li><a href=\"https:\/\/kojihifu.com\/english\/fat-dissolving-injections-tokyo-cost-2\/\" target=\"_blank\" rel=\"noopener\">Fat Dissolving Injections Tokyo: Cost &amp; Treatment Areas<\/a><\/li>\n<li><a href=\"https:\/\/kojihifu.com\/english\/fat-dissolving-injections-tokyo-english\/\" target=\"_blank\" rel=\"noopener\">Fat Dissolving Injections Tokyo: Cost &amp; English Guide<\/a><\/li>\n<li><a href=\"https:\/\/kojihifu.com\/english\/fat-dissolving-thighs-arms-tokyo\/\" target=\"_blank\" rel=\"noopener\">Fat Dissolving for Thighs and Arms Tokyo: Treatment Guide<\/a><\/li>\n<li><a href=\"https:\/\/kojihifu.com\/english\/fat-dissolving-belly-tokyo-results\/\" target=\"_blank\" rel=\"noopener\">Fat Dissolving for Belly Tokyo: Results Guide<\/a><\/li>\n<li><a href=\"https:\/\/kojihifu.com\/english\/kybella-vs-bnls-tokyo-comparison\/\" target=\"_blank\" rel=\"noopener\">KYBELLA vs BNLS Tokyo: Double Chin Injection Comparison<\/a><\/li>\n<\/ul>\n<div style=\"margin: 2.5em 0 1em; padding: 1.5em; border: 1px solid #d5d5d5; border-radius: 10px; background: #fafafa; font-size: .9em;\">\n<p style=\"font-size: .72em; font-weight: bold; color: #888; margin: 0 0 1.2em; letter-spacing: .08em;\">SUPERVISED BY<\/p>\n<div style=\"display: flex; align-items: flex-start; gap: 1.2em; flex-wrap: wrap;\">\n<div style=\"flex-shrink: 0; text-align: center; min-width: 110px;\"><img decoding=\"async\" style=\"width: 100px; height: 100px; border-radius: 50%; object-fit: cover; object-position: top center; display: block; margin: 0 auto; border: 3px solid #e0e0e0;\" src=\"https:\/\/kojihifu.com\/hon\/wp-content\/uploads\/2022\/01\/photo-karibejun-400-3_re-300x300.jpg\" alt=\"Dr. Jun Karibe MD \u2014 Board-certified Plastic Surgeon, Director of Kojimachi Dermatology &amp; Plastic Surgery Clinic\" \/><\/p>\n<p style=\"margin: .6em 0 .1em; font-weight: bold; font-size: .95em; color: #222;\">Dr. Jun Karibe<\/p>\n<p style=\"margin: 0 0 .1em; font-size: .75em; color: #999;\">MD<\/p>\n<p style=\"margin: 0; font-size: .75em; color: #555; font-weight: bold;\">Director<\/p>\n<\/div>\n<div style=\"flex: 1; min-width: 200px;\">\n<div style=\"margin-bottom: .75em; background: #fff; border: 1px solid #ebebeb; border-radius: 6px; padding: .7em 1em;\">\n<p style=\"margin: 0 0 .35em; font-size: .78em; font-weight: bold; color: #666; border-bottom: 1px solid #f2f2f2; padding-bottom: .3em;\">Education &amp; Career<\/p>\n<div style=\"font-size: .82em; color: #444; line-height: 1.75;\">\n<div>Juntendo University School of Medicine<\/div>\n<div>Department of Plastic Surgery, University of Tokyo Hospital<\/div>\n<div>Assistant Professor, Plastic &amp; Cosmetic Surgery, Saitama Medical University<\/div>\n<div>Assistant Professor &amp; Chief Resident, Yamanashi University Hospital<\/div>\n<div>2019: Founded Kojimachi Dermatology &amp; Plastic Surgery Clinic (Ichigaya, Tokyo)<\/div>\n<div>2021: Founded BIOTOPE CLINIC Shirokanedai (Minato-ku, Tokyo)<\/div>\n<\/div>\n<\/div>\n<div style=\"margin-bottom: .75em; background: #fff; border: 1px solid #ebebeb; border-radius: 6px; padding: .7em 1em;\">\n<p style=\"margin: 0 0 .35em; font-size: .78em; font-weight: bold; color: #666; border-bottom: 1px solid #f2f2f2; padding-bottom: .3em;\">Certifications<\/p>\n<div style=\"font-size: .82em; color: #444; line-height: 1.75;\">\n<div>Board-certified Plastic Surgeon \u2014 Japan Society of Plastic and Reconstructive Surgery<\/div>\n<div>Specialist \u2014 Japan Society of Anti-Aging Medicine<\/div>\n<div>Certified Industrial Physician \u2014 Japan Medical Association<\/div>\n<div>Allergan VST-certified Injector (Botox &amp; Hyaluronic Acid)<\/div>\n<\/div>\n<\/div>\n<div style=\"background: #fff; border: 1px solid #ebebeb; border-radius: 6px; padding: .7em 1em;\">\n<p style=\"margin: 0 0 .35em; font-size: .78em; font-weight: bold; color: #666; border-bottom: 1px solid #f2f2f2; padding-bottom: .3em;\">Awards<\/p>\n<div style=\"font-size: .82em; color: #444; line-height: 1.75;\">\n<div>Best Presentation Award \u2014 Dept. of Plastic Surgery, University of Tokyo (2016)<\/div>\n<div>Excellence Award \u2014 Japan Society of Plastic and Reconstructive Surgery (2018)<\/div>\n<div>Featured Presentation \u2014 ASPS Annual Scientific Meeting, USA (2018)<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div style=\"margin-top: 1em; padding-top: .75em; border-top: 1px solid #e8e8e8; display: flex; flex-wrap: wrap; align-items: center; gap: .5em;\"><a style=\"display: inline-block; background: #e1306c; color: #fff; padding: .4em .9em; border-radius: 4px; text-decoration: none; font-size: .8em; font-weight: bold;\" href=\"https:\/\/www.instagram.com\/dr.jun_\/\" target=\"_blank\" rel=\"noopener noreferrer\">Instagram<\/a><\/p>\n<div style=\"margin-top: 1em; padding-top: .75em; border-top: 1px dashed #d5d5d5; font-size: .78em; color: #555; line-height: 1.7;\">\n<p style=\"margin: 0 0 .3em; font-size: .72em; font-weight: bold; color: #888; letter-spacing: .08em;\">MEDICAL REVIEW<\/p>\n<div><strong>Jun Karibe, MD<\/strong> \u2014 Board-certified Plastic Surgeon \u2014 Japan Society of Plastic and Reconstructive Surgery<\/div>\n<div>Medical Director, BIOTOPE CLINIC<\/div>\n<div>Last medically reviewed: 2026-09-03<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"Fat dissolving injection in Tokyo: what it costs, which areas are treated, realistic results and downtime, plus who is a candidate. Ask our English team.","protected":false},"author":4,"featured_media":11711,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20,21],"tags":[886,887,888,623,523,341,26],"class_list":["post-11712","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cosmetic-treatments","category-skin-dermatology","tag-fat-dissolving-injection-2","tag-deoxycholic-acid","tag-injection-lipolysis","tag-double-chin","tag-submental-fat","tag-body-contouring","tag-tokyo-clinic"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/posts\/11712","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/comments?post=11712"}],"version-history":[{"count":1,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/posts\/11712\/revisions"}],"predecessor-version":[{"id":11731,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/posts\/11712\/revisions\/11731"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/media\/11711"}],"wp:attachment":[{"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/media?parent=11712"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/categories?post=11712"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/tags?post=11712"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}