{"id":12790,"date":"2026-10-10T13:35:46","date_gmt":"2026-10-10T04:35:46","guid":{"rendered":"https:\/\/kojihifu.com\/english\/?p=12790"},"modified":"2026-10-10T13:35:47","modified_gmt":"2026-10-10T04:35:47","slug":"artmake-pain-safety-side-effects-4","status":"publish","type":"post","link":"https:\/\/kojihifu.com\/english\/artmake-pain-safety-side-effects-4\/","title":{"rendered":"Artmake Pain, Safety &#038; Side Effects: A Patient Guide"},"content":{"rendered":"<p><script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"MedicalWebPage\",\"@id\":\"https:\/\/kojihifu.com\/english\/artmake-pain-safety-side-effects\/#webpage\",\"url\":\"https:\/\/kojihifu.com\/english\/artmake-pain-safety-side-effects\/\",\"name\":\"Artmake Pain, Safety & Side Effects: A Patient Guide\",\"inLanguage\":\"en\",\"isPartOf\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#website\"},\"about\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#clinic-biotope\"},\"reviewedBy\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#physician-karibe\"},\"lastReviewed\":\"2026-10-07\"},{\"@type\":[\"Article\",\"MedicalWebPage\"],\"@id\":\"https:\/\/kojihifu.com\/english\/artmake-pain-safety-side-effects\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/kojihifu.com\/english\/artmake-pain-safety-side-effects\/#webpage\"},\"headline\":\"Artmake Pain, Safety & Side Effects: A Patient Guide\",\"url\":\"https:\/\/kojihifu.com\/english\/artmake-pain-safety-side-effects\/\",\"inLanguage\":\"en\",\"author\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#physician-karibe\"},\"reviewedBy\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#physician-karibe\"},\"publisher\":{\"@id\":\"https:\/\/kojihifu.com\/english\/#organization\"},\"mainEntityOfPage\":{\"@id\":\"https:\/\/kojihifu.com\/english\/artmake-pain-safety-side-effects\/#webpage\"},\"description\":\"Artmake pain, safety and side effects explained for English-speaking patients in Japan. Learn what to expect, risks, and how Japan's medical rules protect you.\",\"datePublished\":\"2026-10-07\",\"dateModified\":\"2026-10-07\",\"lastReviewed\":\"2026-10-07\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/kojihifu.com\/english\/artmake-pain-safety-side-effects\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/kojihifu.com\/english\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Skin & Dermatology\",\"item\":\"https:\/\/kojihifu.com\/english\/column\/skin-dermatology\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Artmake Pain, Safety & Side Effects: A Patient Guide\",\"item\":\"https:\/\/kojihifu.com\/english\/artmake-pain-safety-side-effects\/\"}]}]}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"How long does artmake last?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Results are semi-permanent and typically require a refresh after one to three years, depending on skin type, lifestyle, and sun exposure. A touch-up session is generally scheduled four to eight weeks after the initial procedure, with maintenance recommended as fading occurs over subsequent years.\"}}, {\"@type\": \"Question\", \"name\": \"Can I have an MRI scan after artmake?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"The U.S. Food and Drug Administration notes rare reports of mild swelling or burning sensations in tattooed facial areas during MRI head scans. Always inform the radiologist and MRI technician that you have artmake before your scan. Modern facilities are well versed in managing patients with cosmetic tattooing and can advise on any precautions.\"}}, {\"@type\": \"Question\", \"name\": \"What if I am not satisfied with the colour or shape?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Artmake can be lightened or removed using laser treatment, though complete removal is not always achievable and may require multiple sessions. Because correction carries its own time and cost, a detailed pre-procedure consultation \u2014 during which colour, shape, and technique are agreed \u2014 is a standard and important part of the process at BIOTOPE CLINIC.\"}}, {\"@type\": \"Question\", \"name\": \"Is artmake safe for sensitive skin?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"A patch test of the intended pigment can be arranged before the procedure to screen for adverse reactions. A 2021 clinical study from a Tokyo artmake clinic found no allergic reactions to standard inorganic pigments in 1,352 patients, though individual responses vary. Disclose your full skin history at the consultation so the treating physician can assess suitability and recommend the most appropriate pigment formulation.\"}}]}<\/script><\/p>\n<h2>What Is Artmake?<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Artmake pain, safety and side effects: what Englis \u2014 What Is Artmake\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/10\/pexels_16057715_1791332782.webp\" alt=\"Artmake pain, safety and side effects: what Englis \u2014 What Is Artmake\" \/><\/figure>\n<p>Artmake (\u30a2\u30fc\u30c8\u30e1\u30a4\u30af) is the Japanese term for medical permanent makeup \u2014 a cosmetic procedure in which pigment is deposited into the superficial layers of the skin to create long-lasting enhancements to the eyebrows, eyelids, or lips. In English, the same procedure may be called micropigmentation, cosmetic tattooing, or permanent makeup.<\/p>\n<p>Unlike a conventional body tattoo, which drives pigment deep into the dermis, artmake targets the uppermost dermal layers. This shallower placement means the results are semi-permanent rather than lifelong: depending on skin type, sun exposure, and lifestyle, artmake typically fades over one to three years, at which point a touch-up session is advisable.<\/p>\n<p>In Japan, artmake is legally classified as a <strong>medical act<\/strong> under Article 17 of the Medical Practitioners&#8217; Act (\u533b\u5e2b\u6cd5). The Ministry of Health, Labour and Welfare has issued official notifications confirming that introducing pigment into the skin via needle constitutes a medical practice that may only be performed by a licensed physician or a nurse working under physician supervision. This regulatory framework is a meaningful patient safety advantage that distinguishes Japan from many other countries.<\/p>\n<table style=\"border-collapse: collapse; width: 100%; margin: 20px 0; font-size: 0.95em; border: 1px solid #ccc;\">\n<thead>\n<tr>\n<th style=\"border: 1px solid #ccc; padding: 10px 12px; background: #f1faf3; text-align: left; font-weight: bold;\">Feature<\/th>\n<th style=\"border: 1px solid #ccc; padding: 10px 12px; background: #f1faf3; text-align: left; font-weight: bold;\">Artmake (Japan)<\/th>\n<th style=\"border: 1px solid #ccc; padding: 10px 12px; background: #f1faf3; text-align: left; font-weight: bold;\">Microblading<\/th>\n<th style=\"border: 1px solid #ccc; padding: 10px 12px; background: #f1faf3; text-align: left; font-weight: bold;\">Conventional tattoo<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Technique<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Machine-driven fine needle(s)<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Manual blade \u2014 eyebrows only<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Machine-driven needle<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Skin depth<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Superficial dermis<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Superficial dermis<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Deep dermis<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Longevity<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">1\u20133 years (semi-permanent)<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">1\u20132 years (semi-permanent)<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Decades (permanent)<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Areas treated<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Brows, eyelids, lips<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Eyebrows only<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Any body area<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Legal status in Japan<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Medical act \u2014 physician only<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Medical act \u2014 physician only<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Governed by separate regulation<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Reversal<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Laser removal possible, not guaranteed<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Laser removal possible, not guaranteed<\/td>\n<td style=\"border: 1px solid #ccc; padding: 10px 12px; vertical-align: top;\">Very difficult to remove<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>How Artmake Works \u2014 Technique and Pain<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Artmake pain, safety and side effects: what Englis \u2014 How Artmake Works \u2014 Technique and Pain\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/10\/pexels_8826403_1791332783.webp\" alt=\"Artmake pain, safety and side effects: what Englis \u2014 How Artmake Works \u2014 Technique and Pain\" \/><\/figure>\n<h3>The procedure<\/h3>\n<p>A licensed physician or nurse uses a fine digital pen device to deposit pigment into the uppermost dermis with precisely controlled depth and speed. The practitioner works across the treatment area in methodical passes, building colour and definition gradually. A single area \u2014 such as the eyebrows \u2014 typically takes 60\u201390 minutes, inclusive of anaesthetic application time.<\/p>\n<h3>Numbing and pain management<\/h3>\n<p>A topical anaesthetic cream is applied to the treatment area and left in place for 20\u201330 minutes before the procedure begins. Most patients describe the sensation as a mild scratching or vibrating pressure rather than sharp pain. Tolerance varies between individuals, and the eyelid and lip areas tend to be more sensitive than the brow area.<\/p>\n<p>Describing artmake as &#8220;painless&#8221; is not accurate. The anaesthetic cream reduces sensation substantially, but some awareness of the procedure is normal and expected. A thorough pre-procedure consultation gives patients the opportunity to discuss pain management and address concerns before the appointment.<\/p>\n<h3>Medications to declare<\/h3>\n<p>Inform your doctor if you are taking blood-thinning agents \u2014 including regular use of aspirin or ibuprofen \u2014 anticoagulant therapy, or topical or oral retinoids. These can affect bleeding, pigment uptake, and healing.<\/p>\n<h2>Side Effects and Safety \u2014 What the Evidence Shows<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Artmake pain, safety and side effects: what Englis \u2014 Side Effects and Safety \u2014 What the Evidence Shows\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/10\/pexels_5128265_1791332784.webp\" alt=\"Artmake pain, safety and side effects: what Englis \u2014 Side Effects and Safety \u2014 What the Evidence Shows\" \/><\/figure>\n<h3>Documented complication rates<\/h3>\n<p>A 2021 clinical study published in the journal <em>Medicine<\/em> (Tomita et al.) surveyed 1,352 patients who received eyebrow and eyeline artmake at the Shibuya Mori Clinic in Tokyo between 2016 and 2020, using inorganic pigments including iron oxide and titanium dioxide. Key findings were:<\/p>\n<ul>\n<li>Overall complication rate: <strong>12.1%<\/strong> \u2014 with no complications persisting at follow-up<\/li>\n<li>Eyebrow procedures \u2014 most common complication: itching, in <strong>8.2%<\/strong> of patients<\/li>\n<li>Eyeline procedures \u2014 most common complication: swelling, in <strong>13.2%<\/strong> of patients<\/li>\n<li>Local infections: <strong>0.2%<\/strong> (3 cases across 1,352 patients)<\/li>\n<li>Allergic reactions to the inorganic pigments used: none detected<\/li>\n<li>Patient satisfaction with the aesthetic outcome: <strong>89.6%<\/strong><\/li>\n<\/ul>\n<p>The Cleveland Clinic describes the ordinary reactions following micropigmentation as a small amount of bleeding, swelling, and crusting \u2014 all of which are temporary and expected.<\/p>\n<h3>Less common but important risks<\/h3>\n<p>The U.S. Food and Drug Administration documents the following risks for permanent makeup procedures: allergic reactions, granuloma formation (nodules that can develop months or even years after the procedure as the body responds to pigment particles), keloid scarring in predisposed individuals, increased sunburn sensitivity in the treated area, and \u2014 in rare cases \u2014 swelling or burning sensations in tattooed facial areas during MRI head scans.<\/p>\n<p>For <strong>eyeliner artmake specifically<\/strong>, the Cleveland Clinic highlights the risk of ectropion (the eyelid turning away from the eyeball), loss of eyelashes, crusting, and eyelid injury if the procedure is not performed with appropriate precision. This underlines why selecting a physician-led clinical environment is particularly important for eye-area procedures.<\/p>\n<h3>Common misconceptions<\/h3>\n<p><strong>Misconception: Artmake is the same as a regular tattoo.<\/strong><br \/>\nArtmake places pigment in the superficial dermis, whereas conventional tattooing penetrates to a much greater depth. Because the upper skin layers regenerate over time, artmake fades and requires periodic maintenance \u2014 a conventional tattoo does not. In Japan, artmake is separately classified as a regulated medical act, which carries distinct legal obligations for the practitioner.<\/p>\n<p><strong>Misconception: Artmake is completely painless.<\/strong><br \/>\nTopical anaesthetic cream significantly reduces discomfort, but there is typically some awareness of the procedure, particularly around the eyes and lips. Patients should be cautious of any clinic that promises a fully pain-free experience \u2014 accurate pre-procedure counselling includes a realistic discussion of sensation management.<\/p>\n<h2>Healing and Aftercare<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Artmake pain, safety and side effects: what Englis \u2014 Healing and Aftercare\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/10\/pexels_7446904_1791332785.webp\" alt=\"Artmake pain, safety and side effects: what Englis \u2014 Healing and Aftercare\" \/><\/figure>\n<p>The initial healing phase after artmake takes approximately <strong>one to two weeks<\/strong>. During this period:<\/p>\n<ul>\n<li>The treated area will appear <strong>darker and more defined than the eventual healed result<\/strong> \u2014 this is a normal part of the healing process<\/li>\n<li>Redness, swelling, and light scabbing or flaking are expected, particularly in the first 48\u201372 hours<\/li>\n<li>Picking, rubbing, or peeling the healing skin should be avoided, as this can cause patchy pigment loss<\/li>\n<li>Sensitivity to water is common in the first 7\u201310 days; keeping the area as dry as possible during this window is standard guidance<\/li>\n<\/ul>\n<p>Your treating physician or nurse will provide a written aftercare protocol. Instructions typically include applying a prescribed ointment, avoiding direct sunlight on the treated area, refraining from swimming and saunas, and not applying cosmetics directly over the healing artmake until the skin has fully recovered.<\/p>\n<p>A touch-up session is normally scheduled <strong>four to eight weeks<\/strong> after the initial appointment to assess pigment retention, even out any areas of fading, and refine the result.<\/p>\n<h2>Who Is a Good Candidate?<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Artmake pain, safety and side effects: what Englis \u2014 Who Is a Good Candidate\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/10\/pexels_34607130_1791332786.webp\" alt=\"Artmake pain, safety and side effects: what Englis \u2014 Who Is a Good Candidate\" \/><\/figure>\n<h3>Suitable candidates<\/h3>\n<p>Most healthy adults are suitable candidates for artmake. The procedure is often sought by patients who have sparse or asymmetric eyebrows, have conditions such as alopecia that affect hair growth, find daily makeup application difficult due to dexterity or visual impairment, or are looking for a reliable enhancement that withstands an active lifestyle, sport, or Tokyo&#8217;s climate.<\/p>\n<h3>Contraindications and cautions<\/h3>\n<p>Artmake may not be appropriate for patients with active skin infections or eczema in the treatment area, a documented allergy to topical anaesthetics, a personal history of keloid or hypertrophic scarring, pregnancy or breastfeeding, certain autoimmune conditions or immunosuppressive therapy, or who are currently taking anticoagulants, retinoids, or isotretinoin. The treating physician will review your full medical history and current medications at the consultation and advise accordingly.<\/p>\n<h2>Cost in Tokyo<\/h2>\n<figure style=\"margin: 1.5em 0;\"><img decoding=\"async\" style=\"width: 100%; max-width: 100%; height: auto; border-radius: 8px;\" title=\"Artmake pain, safety and side effects: what Englis \u2014 Cost in Tokyo\" src=\"https:\/\/kojihifu.com\/english\/wp-content\/uploads\/2026\/10\/pexels_3373735_1791332787.webp\" alt=\"Artmake pain, safety and side effects: what Englis \u2014 Cost in Tokyo\" \/><\/figure>\n<p>Because artmake in Japan is a physician-administered medical procedure, it is priced to reflect the clinical setting, practitioner licensing requirements, and the standard of care involved. Costs vary between clinics and depend on the area treated, the technique selected, and the number of sessions required \u2014 most first-time patients need at least two sessions for a complete result.<\/p>\n<p>Please see the <strong>BIOTOPE CLINIC official price page<\/strong> or contact our English-speaking team via LINE or WhatsApp for a current quote. Pricing is confirmed at consultation and may differ from any figures seen on third-party websites.<\/p>\n<div class=\"kjmc-en-booking-inline\" style=\"background: #f7fbf7; border: 1px solid #d5e6d8; border-radius: 10px; padding: 16px 20px; margin: 26px 0; text-align: center;\">\n<p style=\"margin: 0 0 12px; color: #1a3a1f; font-size: 0.95em; line-height: 1.65;\"><strong>Have a question about this treatment?<\/strong><br \/>\nMessage us on LINE or WhatsApp \u2014 our English-speaking team usually replies the same day.<\/p>\n<p style=\"margin: 0; line-height: 1;\"><a style=\"display: inline-flex; align-items: center; gap: 8px; background: #06C755; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/line.me\/R\/ti\/p\/@710uitns?ts=05311801&amp;oat_content=url#~\" target=\"_blank\" rel=\"noopener noreferrer\">Book via LINE<\/a><br \/>\n<a style=\"display: inline-flex; align-items: center; gap: 8px; background: #25D366; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/whatsapp.com\/channel\/0029VbCA1v85K3zY4MLX2a1h\" target=\"_blank\" rel=\"noopener noreferrer\">Message on WhatsApp<\/a><\/p>\n<\/div>\n<h2>Where to Get Artmake in Tokyo \u2014 BIOTOPE CLINIC<\/h2>\n<p>Within our clinic group, artmake is performed at <strong>BIOTOPE CLINIC<\/strong> in Shirokanedai (Minato-ku), directed by Dr. Jun Karibe. Our English-speaking team covers both clinics and handles all English enquiries.<\/p>\n<p>BIOTOPE CLINIC is located at 4-9-10 Shirokanedai, Minato-ku, Tokyo (Green Leaves Building, 2F), one minute on foot from Exit 1 of Shirokanedai Station on the Toei Mita Line. The clinic provides medical artmake for the eyebrows, eyelids, and lips within a fully regulated medical environment.<\/p>\n<p>Kojimachi Dermatology and Plastic Surgery Clinic \u2014 our Ichigaya location in Chiyoda-ku \u2014 does not perform artmake. Because both clinics share the same English-speaking intake team, however, you are welcome to contact either location via LINE or WhatsApp to ask questions, confirm availability, or arrange a consultation at BIOTOPE CLINIC.<\/p>\n<h2>Frequently Asked Questions<\/h2>\n<dl class=\"kj-faq\">\n<dt>Q. How long does artmake last?<\/dt>\n<dd>Results are semi-permanent and typically require a refresh after one to three years, depending on skin type, lifestyle, and sun exposure. A touch-up session is generally scheduled four to eight weeks after the initial procedure, with maintenance recommended as fading occurs over subsequent years.<\/dd>\n<dd><\/dd>\n<dt>Q. Can I have an MRI scan after artmake?<\/dt>\n<dd>The U.S. Food and Drug Administration notes rare reports of mild swelling or burning sensations in tattooed facial areas during MRI head scans. Always inform the radiologist and MRI technician that you have artmake before your scan. Modern facilities are well versed in managing patients with cosmetic tattooing and can advise on any precautions.<\/dd>\n<dd><\/dd>\n<dt>Q. What if I am not satisfied with the colour or shape?<\/dt>\n<dd>Artmake can be lightened or removed using laser treatment, though complete removal is not always achievable and may require multiple sessions. Because correction carries its own time and cost, a detailed pre-procedure consultation \u2014 during which colour, shape, and technique are agreed \u2014 is a standard and important part of the process at BIOTOPE CLINIC.<\/dd>\n<dd><\/dd>\n<dt>Q. Is artmake safe for sensitive skin?<\/dt>\n<dd>A patch test of the intended pigment can be arranged before the procedure to screen for adverse reactions. A 2021 clinical study from a Tokyo artmake clinic found no allergic reactions to standard inorganic pigments in 1,352 patients, though individual responses vary. Disclose your full skin history at the consultation so the treating physician can assess suitability and recommend the most appropriate pigment formulation.<\/dd>\n<\/dl>\n<div class=\"kjmc-en-booking-inline\" style=\"background: #f7fbf7; border: 1px solid #d5e6d8; border-radius: 10px; padding: 16px 20px; margin: 26px 0; text-align: center;\">\n<p style=\"margin: 0 0 12px; color: #1a3a1f; font-size: 0.95em; line-height: 1.65;\"><strong>Have a question about this treatment?<\/strong><br \/>\nMessage us on LINE or WhatsApp \u2014 our English-speaking team usually replies the same day.<\/p>\n<p style=\"margin: 0; line-height: 1;\"><a style=\"display: inline-flex; align-items: center; gap: 8px; background: #06C755; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/line.me\/R\/ti\/p\/@710uitns?ts=05311801&amp;oat_content=url#~\" target=\"_blank\" rel=\"noopener noreferrer\">Book via LINE<\/a><br \/>\n<a style=\"display: inline-flex; align-items: center; gap: 8px; background: #25D366; color: #fff; padding: 10px 20px; border-radius: 8px; text-decoration: none; font-weight: bold; font-size: 0.92em; margin: 4px 6px; white-space: nowrap; vertical-align: middle;\" href=\"https:\/\/whatsapp.com\/channel\/0029VbCA1v85K3zY4MLX2a1h\" target=\"_blank\" rel=\"noopener noreferrer\">Message on WhatsApp<\/a><\/p>\n<\/div>\n<h2>Summary<\/h2>\n<p>Artmake is a semi-permanent cosmetic procedure that in Japan is legally classified as a medical act, performed exclusively by licensed physicians or nurses under physician supervision. When carried out in a qualified medical clinic, published clinical evidence from Tokyo practice shows a low rate of serious complications, a predictable healing window of one to two weeks, and high patient satisfaction. Pain is manageable with topical anaesthetic cream, though some sensation during the procedure is a realistic expectation \u2014 particularly around the eyes and lips.<\/p>\n<p>The most effective safety step you can take is choosing a clinic that operates within Japan&#8217;s regulatory framework, completing a thorough pre-procedure consultation that covers your full medical history, and entering the process with a realistic understanding of expected results and the care they require.<\/p>\n<div class=\"kjmc-en-booking-box\" style=\"background: linear-gradient(135deg,#f1faf3 0%,#e6f3ea 100%); border-radius: 14px; padding: 32px 24px; margin: 36px 0 24px; border: 1px solid #c5dccd; text-align: center;\">\n<h3 style=\"margin: 0 0 8px; color: #3a6e3a; border: none; padding: 0; font-size: 1.3em;\">24\/7 Consultation &amp; Booking<\/h3>\n<div style=\"width: 48px; height: 2px; background: #3a6e3a; margin: 0 auto 22px;\"><\/div>\n<p style=\"margin: 0 0 12px; color: #1a3a1f; font-size: 1.1em; font-weight: bold;\">Book a Consultation or Treatment<\/p>\n<p style=\"margin: 0 0 24px; color: #2c4a35; line-height: 1.75;\">Our English-speaking team responds via LINE or WhatsApp \u2014 usually the same day.<\/p>\n<p style=\"margin: 0 0 10px; line-height: 1;\"><a style=\"display: inline-flex; align-items: center; justify-content: center; gap: 10px; background: #06C755; color: #fff; padding: 14px 32px; border-radius: 10px; text-decoration: none; font-weight: bold; font-size: 1.02em; box-shadow: 0 2px 8px rgba(6,199,85,0.25); min-width: 240px; white-space: nowrap;\" href=\"https:\/\/line.me\/R\/ti\/p\/@710uitns?ts=05311801&amp;oat_content=url#~\" target=\"_blank\" rel=\"noopener noreferrer\">Book via LINE<\/a><\/p>\n<p style=\"margin: 0; line-height: 1;\"><a style=\"display: inline-flex; align-items: center; justify-content: center; gap: 10px; background: #25D366; color: #fff; padding: 14px 32px; border-radius: 10px; text-decoration: none; font-weight: bold; font-size: 1.02em; box-shadow: 0 2px 8px rgba(37,211,102,0.25); min-width: 240px; white-space: nowrap;\" href=\"https:\/\/whatsapp.com\/channel\/0029VbCA1v85K3zY4MLX2a1h\" target=\"_blank\" rel=\"noopener noreferrer\">Message on WhatsApp<\/a><\/p>\n<\/div>\n<h2>References<\/h2>\n<ol>\n<li>Tomita S, Mori K, Yamazaki H, Mori K. Complications of permanent makeup procedures for the eyebrow and eyeline. <em>Medicine.<\/em> 2021;100(18):e25755.<\/li>\n<li>Suleman S, Villegas M, Davis T, Stevens CS, Castaneda P. Chronic granulomatous reaction to semi-permanent eyebrow tint. <em>Cureus.<\/em> 2023; PMC10449613.<\/li>\n<li>Cleveland Clinic. Micropigmentation (permanent makeup): how it&#8217;s done, risks. Cleveland Clinic Medical Encyclopedia; reviewed 2022.<\/li>\n<li>U.S. Food and Drug Administration. Tattoos, temporary tattoos and permanent makeup. FDA.gov. Available at: https:\/\/www.fda.gov\/cosmetics\/cosmetic-products\/tattoos-temporary-tattoos-permanent-makeup<\/li>\n<li>Monolith Law Office. Is permanent makeup considered a medical practice? Understanding the notification from the Ministry of Health, Labour and Welfare that beauty clinics should heed. Monolith Law; 2023.<\/li>\n<\/ol>\n<h2>Related Articles<\/h2>\n<p>You may also find these articles useful.<\/p>\n<ul>\n<li><a href=\"https:\/\/kojihifu.com\/english\/artmake-aftercare-healing-timeline-3\/\" target=\"_blank\" rel=\"noopener\">Artmake Aftercare Guide: Healing Timeline &amp; What to Avoid<\/a><\/li>\n<li><a href=\"https:\/\/kojihifu.com\/english\/eyebrow-artmake-tokyo-cost-guide\/\" target=\"_blank\" rel=\"noopener\">Eyebrow Artmake Tokyo: Cost, Procedure &amp; Clinic Guide<\/a><\/li>\n<li><a href=\"https:\/\/kojihifu.com\/english\/eyeliner-artmake-tokyo-safety-results\/\" target=\"_blank\" rel=\"noopener\">Eyeliner Artmake Tokyo: Safety, Technique &amp; Expected Results<\/a><\/li>\n<li><a href=\"https:\/\/kojihifu.com\/english\/lip-artmake-tokyo-color-healing-results-2\/\" target=\"_blank\" rel=\"noopener\">Lip Artmake Tokyo: Color Choice, Healing &amp; Results Guide<\/a><\/li>\n<li><a href=\"https:\/\/kojihifu.com\/english\/artmake-vs-microblading-vs-tattoo-tokyo-2\/\" target=\"_blank\" rel=\"noopener\">Artmake vs Microblading vs Tattoo: Differences in Tokyo<\/a><\/li>\n<\/ul>\n<div style=\"margin: 2.5em 0 1em; padding: 1.5em; border: 1px solid #d5d5d5; border-radius: 10px; background: #fafafa; font-size: .9em;\">\n<p style=\"font-size: .72em; font-weight: bold; color: #888; margin: 0 0 1.2em; letter-spacing: .08em;\">SUPERVISED BY<\/p>\n<div style=\"display: flex; align-items: flex-start; gap: 1.2em; flex-wrap: wrap;\">\n<div style=\"flex-shrink: 0; text-align: center; min-width: 110px;\"><img decoding=\"async\" style=\"width: 100px; height: 100px; border-radius: 50%; object-fit: cover; object-position: top center; display: block; margin: 0 auto; border: 3px solid #e0e0e0;\" src=\"https:\/\/kojihifu.com\/hon\/wp-content\/uploads\/2022\/01\/photo-karibejun-400-3_re-300x300.jpg\" alt=\"Dr. Jun Karibe MD \u2014 Board-certified Plastic Surgeon, Director of Kojimachi Dermatology &amp; Plastic Surgery Clinic\" \/><\/p>\n<p style=\"margin: .6em 0 .1em; font-weight: bold; font-size: .95em; color: #222;\">Dr. Jun Karibe<\/p>\n<p style=\"margin: 0 0 .1em; font-size: .75em; color: #999;\">MD<\/p>\n<p style=\"margin: 0; font-size: .75em; color: #555; font-weight: bold;\">Director<\/p>\n<\/div>\n<div style=\"flex: 1; min-width: 200px;\">\n<div style=\"margin-bottom: .75em; background: #fff; border: 1px solid #ebebeb; border-radius: 6px; padding: .7em 1em;\">\n<p style=\"margin: 0 0 .35em; font-size: .78em; font-weight: bold; color: #666; border-bottom: 1px solid #f2f2f2; padding-bottom: .3em;\">Education &amp; Career<\/p>\n<div style=\"font-size: .82em; color: #444; line-height: 1.75;\">\n<div>Juntendo University School of Medicine<\/div>\n<div>Department of Plastic Surgery, University of Tokyo Hospital<\/div>\n<div>Assistant Professor, Plastic &amp; Cosmetic Surgery, Saitama Medical University<\/div>\n<div>Assistant Professor &amp; Chief Resident, Yamanashi University Hospital<\/div>\n<div>2019: Founded Kojimachi Dermatology &amp; Plastic Surgery Clinic (Ichigaya, Tokyo)<\/div>\n<div>2021: Founded BIOTOPE CLINIC Shirokanedai (Minato-ku, Tokyo)<\/div>\n<\/div>\n<\/div>\n<div style=\"margin-bottom: .75em; background: #fff; border: 1px solid #ebebeb; border-radius: 6px; padding: .7em 1em;\">\n<p style=\"margin: 0 0 .35em; font-size: .78em; font-weight: bold; color: #666; border-bottom: 1px solid #f2f2f2; padding-bottom: .3em;\">Certifications<\/p>\n<div style=\"font-size: .82em; color: #444; line-height: 1.75;\">\n<div>Board-certified Plastic Surgeon \u2014 Japan Society of Plastic and Reconstructive Surgery<\/div>\n<div>Specialist \u2014 Japan Society of Anti-Aging Medicine<\/div>\n<div>Certified Industrial Physician \u2014 Japan Medical Association<\/div>\n<div>Allergan VST-certified Injector (Botox &amp; Hyaluronic Acid)<\/div>\n<\/div>\n<\/div>\n<div style=\"background: #fff; border: 1px solid #ebebeb; border-radius: 6px; padding: .7em 1em;\">\n<p style=\"margin: 0 0 .35em; font-size: .78em; font-weight: bold; color: #666; border-bottom: 1px solid #f2f2f2; padding-bottom: .3em;\">Awards<\/p>\n<div style=\"font-size: .82em; color: #444; line-height: 1.75;\">\n<div>Best Presentation Award \u2014 Dept. of Plastic Surgery, University of Tokyo (2016)<\/div>\n<div>Excellence Award \u2014 Japan Society of Plastic and Reconstructive Surgery (2018)<\/div>\n<div>Featured Presentation \u2014 ASPS Annual Scientific Meeting, USA (2018)<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div style=\"margin-top: 1em; padding-top: .75em; border-top: 1px solid #e8e8e8; display: flex; flex-wrap: wrap; align-items: center; gap: .5em;\"><a style=\"display: inline-block; background: #e1306c; color: #fff; padding: .4em .9em; border-radius: 4px; text-decoration: none; font-size: .8em; font-weight: bold;\" href=\"https:\/\/www.instagram.com\/dr.jun_\/\" target=\"_blank\" rel=\"noopener noreferrer\">Instagram<\/a><\/p>\n<div style=\"margin-top: 1em; padding-top: .75em; border-top: 1px dashed #d5d5d5; font-size: .78em; color: #555; line-height: 1.7;\">\n<p style=\"margin: 0 0 .3em; font-size: .72em; font-weight: bold; color: #888; letter-spacing: .08em;\">MEDICAL REVIEW<\/p>\n<div><strong>Jun Karibe, MD<\/strong> \u2014 Board-certified Plastic Surgeon \u2014 Japan Society of Plastic and Reconstructive Surgery<\/div>\n<div>Medical Director, BIOTOPE CLINIC<\/div>\n<div>Last medically reviewed: 2026-10-07<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"Artmake pain, safety and side effects explained for English-speaking patients in Japan. Learn what to expect, risks, and how Japan&#8217;s medical rules protect you.","protected":false},"author":4,"featured_media":12789,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,23],"tags":[1073,396,295,224,218,188,26],"class_list":["post-12790","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-skin-dermatology","category-guide-for-foreigners-in-tokyo","tag-medical-beauty","tag-side-effects","tag-eyebrow-tattoo","tag-micropigmentation","tag-permanent-makeup","tag-cosmetic-procedure","tag-tokyo-clinic"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/posts\/12790","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/comments?post=12790"}],"version-history":[{"count":1,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/posts\/12790\/revisions"}],"predecessor-version":[{"id":12853,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/posts\/12790\/revisions\/12853"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/media\/12789"}],"wp:attachment":[{"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/media?parent=12790"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/categories?post=12790"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kojihifu.com\/english\/wp-json\/wp\/v2\/tags?post=12790"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}